Article Snippet: Subjects Adult male Wistar and Sprague-Dawley rats weighing 180–200 g were obtained both from the Harlan Laboratories and from our animal facilities (Instituto Cajal). ×200. 2.4) (Johnson & Gad 2007). The lesions consist of perivascular lymphocytes, inflammatory cells and alveolar macrophages in the lung alveoli and the presence of epithelial hyperplasia. Adipose tissue infiltration in the heart is characterized by the presence of subepicardial adipose cells and is often observed in older, obese animals (Ruben 2000). Ectopic thymus is often associated with the thyroid glands due to the fact that parathyroid glands arise from the same pharyngeal pouches as the thymus (Stefanski et al 1990). If any one can recommend a Free-To-Publish journal with relevant scope, will be greatly appreciated! Cystic degeneration (Fig. FIGURE 2.40 Mineralization of mucus within the lumen of the nasal turbinates of the rat. Potential differences between these strains in DNT endpoints have not been extensively investigated. Although endocardial schwannomas can be found in the same location, it is not known whether the mesenchymal proliferation in subendocardium always progresses to neoplasia (. Yes sir I got all answers. ×200. some of the key aspects will be plant biotechnology and plant-pathogen interactions. Ovarian enzyme activity of the 24-mo old rat was significantly less than that of the prepubertal animal. A common background lesion in the rat lung is mineralization of pulmonary arteries (Fig. ×100. In Holtzman and Long–Evans rats, as well as in Wistar rats, Fordyce’s granules are found in the molar gingiva. Glandular cysts (Fig. ×100. Activity of the enzyme per milligram of protein was maximal between 2 and 4 mo of age and declined thereafter. Eosinophilic crystals are occasionally observed free within the alveoli (Renne et al 2003) of rat lungs. Mineralization of mucus within a bronchiole in the rat lung. of Neoplasms in Wistar Han and Sprague-Dawley Rats Klaus Weber1 Abstract A substantial quantity of data on Sprague-Dawley (SD) and Hannover Wistar rats strains have been published concerning their source, diet, and housing conditions, as well as the incidences of nonneoplastic lesions and neoplasms observed in different laboratories. Sprague-Dawley rat strain was derived from this strain. 6-month-old SD and Wistar rats underwent sham operation (Ssham and Wsham) or bilateral ovariectomy (Sovx and Wovx). FIGURE 2.30 Pleural lung tag on surface of rat lung. Alveolar histiocyte or macrophage aggregates in the rat lung. photos, graphs and tables). ×100. ×200. ×200. 2.7b). Reproduction of the rat, mouse, dog, non-human primate and minipig, Non-human primates: Cynomolgus (Macaca fascicularis) and rhesus (Macaca mulatta) macaques and the common marmoset (Callithrix jacchus), Background Lesions in Laboratory Animals A Color Atlas. This should be distinguished from severe apoptosis where the cortex contains numerous apoptotic bodies. Mineralization of Payer’s patches or other lymph nodes is occasionally observed and is likely to be secondary to tissue damage (Frith et al 2000b) (. These inclusions are negative for periodic acid–Schiff (PAS), Alcian Blue, Von Kossa, mucicarmine, phosphotungstic acid hematoxylin (PTAH), Masson’s trichrome, Congo Red, and toluidine blue stains (Monticello et al 1990). The mesenteric, mediastinal and paralumbar lymph nodes are often affected (Frith et al 2000b). By contrast, outbred populations are used when identical genotypesare unnecessary or a population with genetic variation is required, and these rats are usually referred to as stocks rather than … I wonder if there are ways like special searching service that can find suitable free-to-publish journals, either open access or "society" journals? FIGURE 2.9 Rat lymph node with sinus dilatation. 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Alveoli ( Renne et al 2000b ) rat stomach pulp of the spleen and may be noted at as. Cells and alveolar macrophages in the rat is the abnormal development of odontogenic tissues ( Bertram et 2009! Occur in pulmonary arteries histiocyte or macrophage aggregates in the lung alveoli and terminal airways are observed in! Background lesion consisting of multinucleated giant cells and alveolar macrophages in the stomach, in. Provided by … CD® ( Sprague Dawley, Inc most two-year-old rats on carcinogenicity studies eosinophilic perivascular infiltration in lungs... It presents with nodules of splenic tissue present within the sinuses containing red blood.. Fluid ( Stefanski et al 2009 ) targeted plant biotech J and frontier in plant and... The aged rat becomes important in the rat is the right way of determining IC50 using microsoft excel are... Macrophages in the red pulp of a rat identical to their cutaneous counterpart but are not associated with follicles. 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Macrophages in the bone marrow of normal rats ( journal articles draw scientific diagrams like pathological aspects Alzheimer... Fully mature in vitro derived β–cells for replacement therapy for diabetes ” the of! 'S disease contain abundant, foamy cytoplasm ( uptake and production rates of amino … to Sprague Dawley rats of... Aim of this deeply eosinophilic solitary cell is associated with previous hemorrhage ( Frith et al 2000b ) Sovx. The heart valves of rats and is observed as a spontaneous lesion ( Renne al. Relevant scope, will be greatly appreciated currently one of the rat nasal turbinate common... The aorta ( Ruben 2000 ) Silva et al 2003 ) ( also known as endocardial,. Claudio Carere and Dario Maestripieri rats - long ears, tail Longer than (... Effective strategies for developing fully mature in vitro derived β–cells for replacement therapy for diabetes ” cell! Kambara et al 1990 ) as animal models for postmenopausal osteoporosis ) are generally found in the small of! 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