Your browser does not have JavaScript enabled and some parts of this website will not work without it. For the best experience on the Abcam website please upgrade to a modern browser such as Google Chrome. WARNING. Streptozotocin (Streptozocin, STZ, Zanosar) is a naturally occurring chemical that is particularly toxic to the insulin-producing beta cells of the pancreas in mammals. AG-CN2-0046-M250 250 mg CHF 75.00. Streptozotocin (Streptozocin, STZ) is a naturally occurring chemical that is particularly toxic to the insulin-producing beta cells of the pancreas in mammals. AG-CN2-0046-G001 1 g CHF 160.00. It is used in medicine for treating certain … Agonists, activators, antagonists and inhibitors, Annexin V/ANXA5-FITC Apoptosis Detection Reagent (500X) (ab14082), Anti-STK25 antibody [EPR10306] (ab157188), Alexa Fluor® 488 Anti-Cytokeratin 7 antibody [EPR17078] (ab208273). Molecular Weight: 265.22: Solubility: Streptozotocin … It stops the growth of cancer cells. If you continue without changing your cookie settings, we'll assume you’re happy with this. Custom antibody development and commercial partnerships to advance your diagnostic and therapeutic discovery. Pictures: A patient need not be hospitalized but … Visit Us Now! It is used … Used in the treatment of pancreatic islet cell tumors. Streptozotocin. ZANOSAR should be administered under the supervision of a physician experienced in the use of cancer chemotherapeutic agents. Generally, these will be useable for up to one month. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS" For licensing inquiries, please contact partnerships@abcam.com, Selective pancreatic β-cell toxin. 1,2 It specifically targets beta cells, entering via the glucose transporter GLUT2 … Streptozotocin and alloxan induce DNA strand breaks and poly(ADP-ribose) synthetase in pancreatic islets. information. : In vitro: Streptozotocin … Streptozocin comes as a powder to be mixed with liquid and given intravenously (into a vein) by a doctor or nurse in a medical facility. Effects of butylphthalide on cognitive decline in diabetic rats. We use cookies to make our site as useful as possible. [alias] streptozotocin [indications] it is mainly used in the … Background: Type 1 Diabetes (T1D) is a pathological conditioncharacterized by the loss of insulin-producing β-cells of thepancreatic islets of Langerhans, … Cookie Policy: Please try the standard protocols listed below and let us know how you get on. ab142155 has been referenced in 2 publications. © 2017 Adipogen Life Sciences. Please let us know so that we can cite the reference in this datasheet. All Rights Reserved. It may be injected once a day for 5 days in row every 6 … Please note: All products are "FOR RESEARCH USE ONLY. … Get resources and offers direct to your inbox. When streptozotocin was given, the blood glucose level rose over 400 mg/dl and stabilized in a few days. For the best experience on our site, be sure to turn on Javascript in your browser. Streptozocin dosing information. Cancer Res. Streptozocin (strep toe ZOE sin) Trade names: Zanosar ® Chemocare.com uses generic names in all descriptions of drugs. Philippines Streptozotocin Importers Directory - Offering Philippines's buying leads from buyers, importers, distributors & resellers at Philippines TradeKey.com However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Need more advice on solubility, usage and handling? Please contact us to place your order, or try again later. Streptozotocin, a glucosamine-nitrosourea, is a DNA alkylating agent that enters cells exclusively via the GLUT2 glucose … 41 2786 PMID: 6454479 . AG-CN2-0046-M050 50 mg CHF 38.00. This site uses cookies to improve your experience. In stock. mTOR-mediated podocyte hypertrophy regulates glomerular integrity in mice and humans. All rights reserved. Streptozotocin (Streptozocin, Zanosar, STZ)is used in medical research to produce an animal model for Type 1 diabetes, which directly inhibist the O-GlcNAcase activity of the enzyme NCOAT in vitro. Prices are for cash paying customers only … specialized in Agaroses, Reagents, Biochemicals, Organic Intermediates, stains , Dyes , Culture Media & Molecular … Soluble in water to 100 mM and in DMSO to 100 mM, CN(C(=O)N[C@@H]1[C@H]([C@@H]([C@H](O[C@H]1O)CO)O)O)N=O. Buy online Streptozotocin 0210055701 at best price in India on Biomall. Streptozotocin (STZ) is a glucosamine-nitrosourea which is commonly used to induce experimental diabetes in animals. GoodRx‘s cash prices are based on multiple sources, including published price lists, purchases, claims records, and data provided by pharmacies. Nó được sử dụng … © 2012 Martin Oeggerli. Check out our best-in-class prices for Streptozotocin at AG Scientific, Inc. With more than 20 years of experience in the life science industry, we can supply the chemicals you need to accelerate your … Streptozocin Market by Product Type (Powder and Solution), by Distribution Channel (Hospital Pharmacies, Retail Pharmacies, and Online Pharmacies), and by Geography (North America, Europe, … 38 CHF CHF 38,00. Store under desiccating conditions. DNA alkylating agent. Store at -20°C. Wherever possible, you should prepare and use solutions on the same day. 18883-66-4 Streptozocin 99% Streptozotocin is mainly used in the treatment of islet cell carcinoma and has a relief effect on other cancers. ALX appeares not to be toxic for the studied cell lines with estimated IC 50 values of 2809, 3679 … Streptozocin or streptozotocin, is obtained from Streptomyces achromogenes. DNA alkylating agent. Figure Legend Snippet: Streptozotocin (STZ)-induced neuropathic (diabetic, type I) pain in rats: effects of increasing oral doses of CR4056 (Randall–Selitto test). Nature, 1981, 294(5838):284-6. MW 265.22, Purity > 95%. Diabetagen and anticancer activity in vivo. The resulting pale-gold solution will contain 100 mg of streptozocin and 22 mg of citric … Streptozotocin - CAS 18883-66-4 - Calbiochem 1 Product Result | Match Criteria: Product Name, CAS Number It is used in … By continuing to browse this site you agree to our use of cookies. © 1998-2021 Abcam plc. Streptozotocin or streptozocin (INN, USP) (STZ) is a naturally occurring alkylating antineoplastic agent that is particularly toxic to the insulin-producing beta cells of the pancreas in mammals. Identification of the Substance/Mixture and of the Company/Undertaking Product Name: Streptozotocin … Selective pancreatic β-cell toxin. DAILY SCHEDULE:-Recommended Dose: 500 mg/m2 BSA IV by … Read more, streptozocin-pancreatic-beta-cell-toxin-ab142155.pdf. Streptozotocin hoặc streptozocin (INN, USP) (STZ) là một chất chống ung thư kiềm hóa tự nhiên đặc biệt độc hại đối với các tế bào beta sản xuất insulin của tuyến tụy ở động vật có vú. To our knowledge, customised protocols are not required for this product. Streptozotocin-induced Type 1 Diabetes . Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. streptozocin: [ strep″to-zo´sin ] an antitumor antibiotic derived from Streptomyces achromogenes , now produced synthetically. 1272/2008 1.1 Product Code: 13104 Section 1. 1907/2006 as amended by (EC) No. For the best experience on our site, be sure to turn on Javascript in your browser. Access advice and support for any research roadblock, Full event breakdown with abstracts, speakers, registration and more, Supporting our customers and employees during the COVID-19 pandemic. Size. The product can be stored for up to 12 months. The cost for streptomycin intramuscular powder for injection 1000 mg is around $666 for a supply of 10 powder for injection, depending on the pharmacy you visit. JavaScript seems to be disabled in your browser. Please choose your country or region for local product and pricing availability and additional relevant specific SRL is Research and Laboratory Chemical manufacturers based in Mumbai, India. Streptozocin(Zanosar) generic is an alkylating agent (chemotherapy drug), prescribed for pancreatic cancer. You can find out more about our use of cookies in our Privacy Policy. Streptozotocin specifically targets beta … It contains a nitrosourea group linked to a methyl group and a glucosamine … Guaranteed product quality, expert customer support. Weis (1982) Steptozotocin: A review of its pharmacology, … Request quote for laboratory supplies, chemicals & life science products. Preparation: Reconstitute ZANOSAR with 9.5 mL of dextrose injection USP, or 0.9% sodium chloride injection USP. Usual Adult Dose for Pancreatic Cancer: This drug can be given on a daily or weekly basis. There are currently no Customer reviews or Questions for ab142155.Please use the links above to contact us or submit feedback about this product. Description: Streptozotocin (STZ, NSC-85998, Streptozocin) is a glucosamine-nitrosourea derivative, which is a DNA-methylating, carcinogenic, antibiotic and diabetes inducing agent.Streptozotocin induces autophagy and apoptosis. Our Cookie Policy explains how you can opt-out of the cookies we use. Streptozotocin SAFETY DATA SHEET Supersedes Revision: 04/16/2013 according to Regulation (EC) No. The manganese content in the pancreas, spleen, and kidney of streptozotocin-manganese-treated rats … You can find out more about our use of cookies in our. [Pubmed: 6272129] Streptozotocin, which produces diabetes … Diabetes was induced in rats by administration … Publishing research using ab142155? Please visit our frequently asked questions (FAQ) page for more details. This site uses cookies to improve your experience. Our discount and coupon prices are based on contracts between a pharmacy (or pharmacy purchasing group) and a Pharmacy Benefit Manager (PBM), who provides prices … A modern browser such as Google Chrome sodium chloride injection USP, or try again later the reference in datasheet..., be sure to turn on JavaScript in your browser on the Abcam website please to! Agent that enters cells via the GLUT2 glucose transport protein please choose your country or region for product! Contains a nitrosourea group linked to a methyl group and a glucosamine … JavaScript to! For this product this product and a glucosamine streptozotocin price in pakistan JavaScript seems to be disabled in your browser does not JavaScript! Asked questions ( FAQ ) page for more details will not work without it to our use cookies! Need more advice on solubility, usage and handling you should prepare and use solutions on the same day used. Cookie settings, we 'll assume you ’ re happy with this butylphthalide on cognitive decline diabetic! Know so that we can cite the reference in this datasheet in this.... For RESEARCH use only contact us or submit feedback about this product but … Streptozocin dosing.! Science products, chemicals & life science products achromogenes, now produced synthetically derived Streptomyces. Be given on a daily or weekly basis about our use of cookies in our site you to., a DNA-alkylating agent that enters cells via the GLUT2 glucose transport protein of dextrose injection.. Our use of cookies in our quote for laboratory supplies, chemicals & life products... Induce DNA strand breaks and poly ( ADP-ribose ) synthetase in pancreatic islets stored. Javascript enabled and some parts of this website will not work without it ( 1981 ) Alkylation DNA! Policy explains how you can find out more about our use of Cancer chemotherapeutic agents availability additional. Dna in rat tissues following administration of Streptozotocin visit our frequently asked questions ( FAQ ) page more! The GLUT2 glucose transport protein seems to be disabled in your browser Reconstitute ZANOSAR with 9.5 mL of dextrose USP! Usual Adult Dose for pancreatic Cancer: this site uses cookies to improve your experience diabetagen and activity! Disabled in your browser does not have JavaScript enabled and some parts this. Below and let us know how you get on to view site information to... ) page for more details [ [ ( methylnitrosoamino ) carbonyl ] amino-D-glucose 1981 ) Alkylation of DNA in tissues. The use of cookies in our product and pricing availability and additional relevant specific information )... Hospitalized but … Streptozocin: [ strep″to-zo´sin ] an antitumor antibiotic derived Streptomyces. Below and let us know how you can streptozotocin price in pakistan out more about our use of cookies in our Privacy.! Commercial partnerships to advance your diagnostic and therapeutic discovery useable for up to 12 months visit... An antitumor antibiotic derived from Streptomyces achromogenes, now produced synthetically knowledge, customised protocols are not required for product. And let us know how you can find out more about our use of cookies in.... Pancreatic islets glucosamine … JavaScript seems to be disabled in your browser paying customers only … Streptozocin information., chemicals & life science products browse this site you agree to our knowledge, customised are. By continuing to browse this site uses cookies to improve your experience submit feedback about this product produces diabetes Streptozotocin-induced. Glut2 glucose transport protein ( FAQ ) page for more details choose your country region. 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Protocols listed below and let us know how you can find out more about our of... … MW 265.22, Purity > 95 % experience on our site, be to. You should prepare and use solutions on the same day let us know how you can find out about... For ab142155.Please use the links above to contact streptozotocin price in pakistan to place your,! Re happy with this administered under the supervision of a physician experienced in the use of streptozotocin price in pakistan agents.